Detalhe da pesquisa
1.
Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.
Cell
; 179(6): 1319-1329.e8, 2019 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31704029
2.
Author Correction: mTOR at the nexus of nutrition, growth, ageing and disease.
Nat Rev Mol Cell Biol
; 21(4): 246, 2020 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-32005970
3.
mTOR at the nexus of nutrition, growth, ageing and disease.
Nat Rev Mol Cell Biol
; 21(4): 183-203, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31937935
4.
mTOR Signaling in Growth, Metabolism, and Disease.
Cell
; 168(6): 960-976, 2017 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28283069
5.
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.
Cell
; 168(5): 890-903.e15, 2017 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28162770
6.
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Cell
; 169(2): 258-272.e17, 2017 Apr 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28388410
7.
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.
Cell
; 171(3): 642-654.e12, 2017 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29053970
8.
Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism.
Cell
; 166(5): 1324-1337.e11, 2016 Aug 25.
Artigo
Inglês
| MEDLINE | ID: mdl-27565352
9.
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Cell
; 165(1): 153-164, 2016 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-26972053
10.
Nutrient-sensing mechanisms across evolution.
Cell
; 161(1): 67-83, 2015 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25815986
11.
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Cell
; 162(3): 540-51, 2015 Jul 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26232224
12.
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
Cell
; 158(5): 1094-1109, 2014 Aug 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25171410
13.
Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.
Nature
; 608(7921): 209-216, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35859173
14.
Structure of the nutrient-sensing hub GATOR2.
Nature
; 607(7919): 610-616, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35831510
15.
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Nature
; 609(7929): 1005-1011, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36131016
16.
mTOR signaling in growth control and disease.
Cell
; 149(2): 274-93, 2012 Apr 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22500797
17.
mTOR Signaling in Growth, Metabolism, and Disease.
Cell
; 169(2): 361-371, 2017 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28388417
18.
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
Cell
; 150(6): 1196-208, 2012 Sep 14.
Artigo
Inglês
| MEDLINE | ID: mdl-22980980
19.
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase.
Immunity
; 46(6): 1045-1058.e6, 2017 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28636954
20.
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Cell
; 146(3): 408-20, 2011 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21816276